| CAS No.: | 1187594-09-7 |
|---|---|
| Formula: | C16h17n7o2s |
| EINECS: | 691-421-4 |
| Type: | Pharmaceutical Intermediates |
| Appearance: | Powder |
| Quality: | Technical |
| Customization: |
|---|
Suppliers with verified business licenses
Audited Supplier Product Name: Baricitinib
Synonyms: 1-(Ethylsulfonyl)-3-[4-(7H-pyrrolo[2,3-d]pyriMidin-4-yl)-1H-pyrazol-1-yl]-3-azetidineacetoni trile;Baricitinib;INCB 028050;LY 3009104;BARICITINIB;INCB28050;LY3009104;Baricitinib (LY3009104);2-(3-(4-(3H-Pyrrolo[2,3-d]pyriMidin-4-yl)-1H-pyrazol-1-yl)-1-(ethylsulfonyl)azetidin-3-yl)acetoni trile;Baricitinib/INCB 028050/LY3009104
CAS: 1187594-09-7
MF: C16H17N7O2S
MW: 371.42
EINECS: 691-421-4
Description:
The oral, targeted synthetic DMARD (tsDMARD), JAK1 and JAK2 inhibitor baricitinib (Olumiant) is a novel small molecule that is approved in the EU[3] and Japan for the treatment of adults with rheumatoid arthritis RA (moderate or severe active[3]), who responded inadequately to (other treatments) or who were intolerant of C1 DMARD. JAK is a tyrosine kinase that plays crucial roles in cytokine receptor binding-triggered signal transduction activating the transcription factor signal transducers and activator of transcription (STAT). Activation of the receptor-bound JAKs is critical for initiating phosphorylation of the cytokine receptor and subsequent recruitment of one or more STATs. The phosphorylated STAT dimer is then actively and directly transported to the nucleus without involvement of any other kinases.
Usage:
Baricitinib is a JAK1 and JAK2 inhibitor and have been used as a promising treatment for rheumatoid arthritis.
1. Rich experience: Our company is a professional production leading factory in China in pharmaceutical area of many years.
2. Top quality: High quality guaranteed, once any problem is found, the package would be reshipped for you .
3. Security Shipping: Shipping by express (FedEx,UPS,DHL,EMS), by air. The most professional forwarder would be recommanded for you.
4. Fast delivery: We have stock, so we can delivery quickly once payment is received.
5. Quality service: We will give you warm after-sale service,if any question we will reply you within 24 hours.
6. Competitive prices: A discount would be given when you make a large order.
| Make an order | Please make clear what product and what quantity you need |
| Quote | Prices and Specifications details would be offered for you to consider and confirm |
| Payment ways | Bank Transfer, Western Union, Money Gram and Bitcoin |
| Delivery ways | All Express Modes(EMS, DHL, TNT, FedEx, UPS, etc.) |
| Shipping address | Provide your Valid and Correct destination address info(if possible with post code, phone number). |
| Packing | Select best ways according to quantity and safety degree(Super discreet, professional and experienced) |
| Lead time | Within 8 hours upon receipt of payment |
| Package picture | Photos of package would be offered to tell apart the items |
| Tracking number | Offered once it is released |
| Shipping time | 3-7 working days (Door-to-Door) |
| After-sale service | 24/7 Online for any problems |
Our factory:
Our laboratory:
Our warehouse:
Hubei Yuanmeng Biological Technology Co., Ltd., which is located in Wuhan, China. We are specializing in the exportation of APIs, and plant extracts ect.
Our products has been exported to America, Australia, Brazil, the Europe, Middle East and other areas in the world. We have established close and stable cooperative relationships with over 200 domestic pharmaceutical and chemical enterprises. With high quality and favorable price, we′ re pleased to get your inquiry and we will reply you as soon as possible.
We will continue to forge ahead and strive hard for excellence, keep on exploring and progressing to develop more high-tech products with superior quality, to satisfy increasing demand of the clients, and create more value for our partners!
Contact us!
Hubei Yuanmeng Biological Technology Co., Ltd.
Room 3820, Building 2, Vanke Golden City, Hongshan District, Wuhan, Hubei, China
Fiona Wei
Suppliers with verified business licenses
Audited Supplier 
){kind=link}
){kind=link}