• High Purity Crisaborole CAS 906673-24-3 Crisaborole Powder with Best Price
  • High Purity Crisaborole CAS 906673-24-3 Crisaborole Powder with Best Price
  • High Purity Crisaborole CAS 906673-24-3 Crisaborole Powder with Best Price
  • High Purity Crisaborole CAS 906673-24-3 Crisaborole Powder with Best Price
  • High Purity Crisaborole CAS 906673-24-3 Crisaborole Powder with Best Price
  • High Purity Crisaborole CAS 906673-24-3 Crisaborole Powder with Best Price

High Purity Crisaborole CAS 906673-24-3 Crisaborole Powder with Best Price

CAS No.: 906673-24-3
Formula: C14h10bno3
EINECS: 815-051-1
Type: Pharmaceutical Intermediates
Appearance: Powder
Quality: Technical
Customization:
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  • Overview
  • Product Description
  • Detailed Photos
  • Packaging & Shipping
  • Our Advantages
  • Order Process and Tips
  • About Us
Overview

Basic Info.

Model NO.
CAS 906673-24-3
Colour
White
Product Name
Crisaborole
Other Name
Crisaborole Powder
Molecular Weight
251.05
Melting Point
>130°c
Storage Temp.
Room Temp
Usage
Anti-Inflammatory Agent
Purity
99%Min
Grade
Pharmaceutical Grade
Delivery Time
Within 24 Hours After Receiving The Payment
MOQ
10 Gram
Shipping Method
UPS, FedEx, TNT, EMS Ect
Payment Ways
Western Union, Money Gram, Bitcoin and T/T
Suitable for
Adult
Customized
Non-Customized
Certificate
GMP, ISO 9001
Transport Package
Foil Bag
Specification
1kg/bag
Trademark
yuanmeng
Origin
China
HS Code
2934990002
Production Capacity
1000kg/Month

Product Description

Product Description

Product Name: Crisaborole
Synonyms: 4-[(1,3-Dihydro-1-hydroxy-2,1-benzoxaborol-5-yl)oxy]benzoni trile AN 2728;AN-2728, >=98%;AN2728, Crisaborole;Crisaborole (AN2728);AN 2728;AN2728/AN-2728;4-((1-Hydroxy-1,3-dihydrobenzo-[c][1,2]oxaborol-5-yl)oxy)benzoni trile;4-[(1,3-Dihydro-1-hydroxy-2,1-benzoxaborol-5-yl)oxy]benzoni trile
CAS: 906673-24-3
MF: C14H10BNO3
MW: 251.05
EINECS: 815-051-1
Melting point: >130°C
Boiling point: 425.9±55.0 °C
Density: 1.33±0.1 g/cm3
Storage temp.: room temp
Appearance: White powder

Description:

Crisaborole is a phosphodiesterase- 4 (PDE4) inhibitor that was approved by FDA on December 14, 2016 as Eucrisa, a topical treatment of for mild to moderate atopic dermatitis (AD) in patients aged two years and older. The drug, which was developed by Anacor Pharmaceuticals and later acquired and marketed by Pfizer, is delivered as a 2% ointment, which is applied topically. Its structure contains a boron atom, which facilitates skin penetration and binding to the bimetal center of the phosphodiesterase 4 enzyme. The unique employment of boron within the chemical structure of the drug is designed to enable selective engagement of PDE4 (an enzyme involved in the conversion of cAMP into AMP, which signals for downstream inflammatory events), effective penetration of the drug through human skin, and rapid clearance to limit systemic circulation.

Uses:

A series of phenoxy benzoxaboroles were synthesized and screened for their inhibitory activity against PDE4 and cytokine release. 5-(4-Cyanophenoxy)-2,3-dihydro-1-hydroxy-2,1-benzoxaborole (AN2728) showed potent activity both in vitro and in vivo. AN2728 is being studied as an anti-inflammatory agent.

Detailed Photos

High Purity Crisaborole CAS 906673-24-3 Crisaborole Powder with Best Price

High Purity Crisaborole CAS 906673-24-3 Crisaborole Powder with Best Price

Packaging & Shipping

High Purity Crisaborole CAS 906673-24-3 Crisaborole Powder with Best Price

High Purity Crisaborole CAS 906673-24-3 Crisaborole Powder with Best Price



High Purity Crisaborole CAS 906673-24-3 Crisaborole Powder with Best Price
 

Our Advantages

1. Rich experience: Our company is a professional production leading factory in China in pharmaceutical area of many years. 

2. Top quality: High quality guaranteed, once any problem is found, the package would be reshipped for you .

3. Security Shipping: Shipping by express (FedEx,UPS,DHL,EMS), by air. The most professional forwarder would be recommanded for you.

4. Fast delivery: We have stock, so we can delivery quickly once payment is received.

5. Quality service: We will give you warm after-sale service,if any question we will reply you within 24 hours.

6. Competitive prices: A discount would be given when you make a large order.

Order Process and Tips

 

Make an order Please make clear what product and what quantity you need
Quote Prices and Specifications details would be offered for you to consider and confirm
Payment ways Bank Transfer, Western Union, Money Gram and Bitcoin
Delivery ways All Express Modes(EMS, DHL, TNT, FedEx, UPS, etc.)
Shipping address Provide your Valid and Correct destination address info(if possible with post code, phone number).
Packing Select best ways according to quantity and safety degree(Super discreet, professional and experienced)
Lead time Within 8 hours upon receipt of payment
Package picture Photos of package would be offered to tell apart the items
Tracking number Offered once it is released
Shipping time 3-7 working days (Door-to-Door)
After-sale service 24/7 Online for any problems
 

About Us

Our factory:

High Purity Crisaborole CAS 906673-24-3 Crisaborole Powder with Best Price
Our laboratory:

High Purity Crisaborole CAS 906673-24-3 Crisaborole Powder with Best Price
Our warehouse:

High Purity Crisaborole CAS 906673-24-3 Crisaborole Powder with Best Price


Hubei Yuanmeng Biological Technology Co., Ltd., which is located in Wuhan, China. We are specializing in the exportation of APIs, and plant extracts ect.

Our products has been exported to America, Australia, Brazil, the Europe, Middle East and other areas in the world. We have established close and stable cooperative relationships with over 200 domestic pharmaceutical and chemical enterprises. With high quality and favorable price, we′ re pleased to get your inquiry and we will reply you as soon as possible.

We will continue to forge ahead and strive hard for excellence, keep on exploring and progressing to develop more high-tech products with superior quality, to satisfy increasing demand of the clients, and create more value for our partners!



Contact us!

Hubei Yuanmeng Biological Technology Co., Ltd.
Room 3820, Building 2, Vanke Golden City, Hongshan District, Wuhan, Hubei, China
Fiona Wei 

 
 
 

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Gold Member Since 2020

Suppliers with verified business licenses

Trading Company
Registered Capital
295604.36 USD
Plant Area
40 square meters