Customization: | Available |
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CAS No.: | 34140-59-5 |
Formula: | C26h33no9 |
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Product Name: Trimebutine maleate
Synonyms: 3,4,5-trimethoxybenzoic acid 2-(dimethylamino)-2-phenylbutyl ester maleate;3,4,5-TRIMETHOXYBENZOIC ACID 2-(DIMETHYLAMINO)-2-PHENYLBUTYL ESTER MALEATE SALT;2'-PHENYL-2'-DIMETHYLAMINO-N-BUTYL 3,4,5-TRIMETHOXYBENZOATE MALEATE;2-(dimethylamino)-2-phenylbutyl 3,4,5-trimethoxybenzoate maleate;Cerekinon;Digerent;Modulon;Polibutin
CAS: 34140-59-5
MF: C26H33NO9
MW: 503.54
EINECS: 251-845-9
Melting point: 122-124°C
Boiling point: 329.1±15.0 °C
Density: 1.137±0.06 g/cm3
Storage temp.: 2-8°C
Appearance: White Powder
Description:
Trimebutine maleate has a dual regulatory function on the gastrointestinal tract, regardless of diarrhea or constipation. The pharmacological action is different from the gastrointestinal motility regulator of anticholinergic drugs and antidopamine drugs. The overall improvement rate of abdominal distension, abdominal pain, nausea, and belching was 64.1%. The overall improvement rate of irritable bowel syndrome with abnormal bowel and digestive system symptoms was 56.5%. For vomiting induced by copper sulfate, this product can significantly prolong the time required to induce vomiting after intravenous injection of 3mg/k Chemicalbookg or oral 60mg/kg. Absorption and blood concentration In a healthy adult man, 30 minutes after oral administration of 100 mg trimebutine maleate, the blood concentration reached the highest value of 32.5-42.3 mg/ml, and t1/2 was 2 hours. After oral administration of this product in adults, it is hydrolyzed and demethylated at the N position to form a conjugate, which is excreted in urine. The excretion rate of unchanged substances in urine within 24 hours is below 0.01%.
Uses:
Opioid receptor agonist. Antispasmodic
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Hubei Yuanmeng Biological Technology Co., Ltd., which is located in Wuhan, China. We are specializing in the exportation of APIs, and plant extracts ect.
Our products has been exported to America, Australia, Brazil, the Europe, Middle East and other areas in the world. We have established close and stable cooperative relationships with over 200 domestic pharmaceutical and chemical enterprises. With high quality and favorable price, we′ re pleased to get your inquiry and we will reply you as soon as possible.
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Hubei Yuanmeng Biological Technology Co., Ltd.
Room 3820, Building 2, Vanke Golden City, Hongshan District, Wuhan, Hubei, China
Fiona Wei