CAS No.: | 107007-99-8 |
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Formula: | C18h25cln4o |
EINECS: | 634-603-0 |
Type: | Pharmaceutical Intermediates |
Appearance: | Powder |
Quality: | Technical |
Customization: |
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Product Name: Granisetron Hydrochloride
CAS: 107007-99-8
MF: C18H25ClN4O
MW: 348.87
EINECS: 634-603-0
Melting point: 290-292°C
Storage temp.: Room temp
Description:
Granisetron hydrochloride is the second selective 5HT-3-antagonist approved for the management of nausea and vomiting induced by cancer chemotherapy.Like ondansetron, granisetron hydrochloride is superior to metoclopramide in both efficacy and side effect profile. The compound appears to be effective both as a prophylactic agent and in blocking vomiting once started.
Usage:
A specific serotonin (5HT3) receptor antagonist. Used as an antiemetic. Granisetron HCl is a serotonin 5-HT3 receptor antagonist used as an antiemetic to treat nausea and vomiting following chemothera py. Its main effect is to reduce the activity of the vagus nerve. It does not have much effect on vomiting due to motion sickness. This drug does not have any effect on dopamine receptors or muscarini c receptor
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Fiona Wei / CEO
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