CAS No.: | 139504-50-0 |
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Formula: | C35h48cln3o10s |
EINECS: | 603-999-7 |
Type: | Pharmaceutical Intermediates |
Appearance: | Powder |
Quality: | Technical |
Customization: |
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Product Name: Mertansine
Synonyms: N2'-deacetyl-N2'-(3-Mercapto-1-oxopropyl)-Maytansine;Maytansinoid dM 1;Maytansine, N2'-deacetyl-N2'-(3-mercapto-1-oxopropyl)-;DM1 Compound;MERTANSINE; DM 1; MAYTANSINOID DM 1; 139504-50-0; UNII-DDZ29HGH0E; DM1 COMPOUND;;UNII-DDZ29HGH0E;DM1 Mertansine;Maytansine DM1
CAS: 139504-50-0
MF: C35H48ClN3O10S
MW: 738.29
EINECS: 603-999-7
Melting point: 190-192ºC
Boiling point: 937.1±65.0 °C
Density: 1.33±0.1 g/cm3
Storage temp.: 2-8°C
Appearance: White powder
Description:
Maytansine, a natural alkaloid, was first isolated from Maydens ovale in 1972 and exists in the genus Maydens of the family Weedaceae and its relatives. The mechanism of action of maytansine, acting on microtubules and tubulin, blocks the formation of spindles in the process of cell mitosis by inhibiting the depolymerization of cell microtubules, and has a strong ability to inhibit tumor cell proliferation.
Uses:
Mertansine (DM1) is a microtubulin inhibitor which binds at the tips of microtubules and suppresses the dynamicity of microtubules.. Mertansine is an antibody-conjugatable maytansinoid that was developed to overcome systemic toxicity associated with maytansine and to enhance tumor-specific delivery. It can be attached to a monoclonal antibody with a linker to create an antibody-drug conjugate (ADC).
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Shipping time | 3-7 working days (Door-to-Door) |
After-sale service | 24/7 Online for any problems |
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Hubei Yuanmeng Biological Technology Co., Ltd., which is located in Wuhan, China. We are specializing in the exportation of APIs, and plant extracts ect.
Our products has been exported to America, Australia, Brazil, the Europe, Middle East and other areas in the world. We have established close and stable cooperative relationships with over 200 domestic pharmaceutical and chemical enterprises. With high quality and favorable price, we′ re pleased to get your inquiry and we will reply you as soon as possible.
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Hubei Yuanmeng Biological Technology Co., Ltd.
Room 3820, Building 2, Vanke Golden City, Hongshan District, Wuhan, Hubei, China
Fiona Wei
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